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ESM-2 is a state-of-the-art protein model trained on a masked language modelling objective. It is suitable for fine-tuning on a wide range of tasks that take protein sequences as input. For detailed information on the model architecture and training data, please refer to the accompanying paper. You may also be interested in some demo notebooks (PyTorch, TensorFlow) which demonstrate how to fine-tune ESM-2 models on your tasks of interest. Several ESM-2 checkpoints are available in the Hub with varying sizes. Larger sizes generally have somewhat better accuracy, but require much more memory and time to train:

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ESM-2 is a state-of-the-art protein model trained on a masked language modelling objective. It is suitable for fine-tuning on a wide range of tasks that take protein sequences as input. For detailed information on the model architecture and training data, please refer to the accompanying paper. You may also be interested in some demo notebooks (PyTorch, TensorFlow) which demonstrate how to fine-tune ESM-2 models on your tasks of interest. Several ESM-2 checkpoints are available in the Hub with varying sizes. Larger sizes generally have somewhat better accuracy, but require much more memory and time to train:

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ESM-2 is a state-of-the-art protein model trained on a masked language modelling objective. It is suitable for fine-tuning on a wide range of tasks that take protein sequences as input. For detailed information on the model architecture and training data, please refer to the accompanying paper. You may also be interested in some demo notebooks (PyTorch, TensorFlow) which demonstrate how to fine-tune ESM-2 models on your tasks of interest. Several ESM-2 checkpoints are available in the Hub with varying sizes. Larger sizes generally have somewhat better accuracy, but require much more memory and time to train:

Text generationOpen weights
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ESM-2 is a state-of-the-art protein model trained on a masked language modelling objective. It is suitable for fine-tuning on a wide range of tasks that take protein sequences as input. For detailed information on the model architecture and training data, please refer to the accompanying paper. You may also be interested in some demo notebooks (PyTorch, TensorFlow) which demonstrate how to fine-tune ESM-2 models on your tasks of interest. Several ESM-2 checkpoints are available in the Hub with varying sizes. Larger sizes generally have somewhat better accuracy, but require much more memory and time to train:

Input Text→ Output Text
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ESM-2 is a state-of-the-art protein model trained on a masked language modelling objective. It is suitable for fine-tuning on a wide range of tasks that take protein sequences as input. For detailed information on the model architecture and training data, please refer to the accompanying paper. You may also be interested in some demo notebooks (PyTorch, TensorFlow) which demonstrate how to fine-tune ESM-2 models on your tasks of interest. Several ESM-2 checkpoints are available in the Hub with varying sizes. Larger sizes generally have somewhat better accuracy, but require much more memory and time to train:

Input Text→ Output Text
Price not verifiedCheck multimodal and channel pricing separately
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ESM-2 is a state-of-the-art protein model trained on a masked language modelling objective. It is suitable for fine-tuning on a wide range of tasks that take protein sequences as input. For detailed information on the model architecture and training data, please refer to the accompanying paper. You may also be interested in some demo notebooks (PyTorch, TensorFlow) which demonstrate how to fine-tune ESM-2 models on your tasks of interest. Several ESM-2 checkpoints are available in the Hub with varying sizes. Larger sizes generally have somewhat better accuracy, but require much more memory and time to train:

Text generationOpen weights
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esmfold_v1

facebook

ESMFold is a state-of-the-art end-to-end protein folding model based on an ESM-2 backbone. It does not require any lookup or MSA step, and therefore does not require any external databases to be present in order to make predictions. As a result, inference time is very significantly faster than AlphaFold2. For details on the model architecture and training, please refer to the accompanying paper. If you're interested in using ESMFold in practice, please check out the associated tutorial notebook.

Text generationOpen weights
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EUPE-ViT-B

facebook

Running AI models on smart edge devices can unlock various user experiences, but presents challenges due to limited compute and the need to handle multiple tasks simultaneously. This requires a vision encoder with small size but powerful and versatile representations. We present our method, Efficient Universal Perception Encoder (EUPE), which offers both inference efficiency and universally good representations for diverse downstream tasks. We achieve this by distilling from multiple domain-expert foundation vision encoders. Unlike previous agglomerative methods that directly scale down from multiple teachers to an efficient encoder, we demonstrate the importance of first scaling up to a large proxy teacher and then distilling from this single teacher. Experiments show that EUPE achieves on-par or better performance than individual domain experts of the same size on diverse task domains and also outperforms previous agglomerative encoders. These are Vision Transformer and ConvNeXt models trained following the method described in the EUPE paper. 6 models are provided: - 3 ViT models including ViT-B16, ViT-S16, ViT-T16 - 3 ConvNeXt models including ConvNeXt-{T/S/B}

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EUPE-ViT-S

facebook

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EUPE-ViT-T

facebook

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FairBERTa

facebook

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