NV-Reason-CT is a 3D vision-language model (VLM) for CT image analysis. It combines a native 3D vision encoder (3D ViT) with a language model and is designed for radiology report generation, general question answering, and multi-step reasoning across chest and abdominal CT volumes. Computed tomography encodes clinically important anatomy across hundreds of slices, yet most vision–language systems either operate on 2D images or compress volumetric features before language decoding. The 3D vision encoder converts a 384×384×384-mm input volume into a 24×24×24 grid of 13,824 visual tokens. All tokens and their corresponding 3D positions are passed to the language model without spatial downsampling, while 3D MRoPE preserves their spatial relationships within the LLM. Input volumes are automatically cropped to the chest or abdomen and resampled to 2-mm isotropic resolution before processing. The model was trained end-to-end using Supervised Fine-Tuning (SFT) and Group Relative Policy Optimization (GRPO) on a curated dataset of approximately 550,000 structured QA examples from 70,111 unique CT volume inputs. The training corpus integrates standardized reports, abnormality-focused QA, multi-turn interactions, and radiologist-authored reasoning collected through recorded and transcribed expert CT interpretations. These expert annotations also guide the generation of report-grounded synthetic reasoning data for SFT, while GRPO uses verifiable rewards over chest and abdominal abnormality sets.

Visual QA

Input Text · Image→ Output Text

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NVIDIA

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Image segmentation

Input Image→ Output Image

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