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KEEP

Astaxanthin · KEEP

**KEEP** (**K**nowledg**E**-**E**nhanced **P**athology) is a foundation model designed for cancer diagnosis that integrates disease knowledge into vision-language pre-training. It utilizes a comprehensive disease knowledge graph (KG) containing 11,454 human diseases and 139,143 disease attributes, such as synonyms, definitions, and hierarchical relationships. KEEP reorganizes millions of publicly available noisy pathology image-text pairs into 143K well-structured semantic groups based on the hierarchical relations of the disease KG. By incorporating disease knowledge into the alignment process, KEEP achieves more nuanced image and text representations. The model is validated on 18 diverse benchmarks with over 14,000 whole-slide images (WSIs), demonstrating state-of-the-art performance in zero-shot cancer diagnosis, including an average sensitivity of 89.8% for cancer detection across 7 cancer types. KEEP also excels in subtyping rare cancers, achieving strong generalizability in diagnosing rare tumor subtypes. We present benchmark results for a range of representative tasks. A complete set of benchmarks can be found in the paper. These results will be updated with each new iteration of KEEP. Validated on 18 diverse benchmarks with more than 14,000 whole slide images (WSIs), KEEP achieves state-of-the-art performance in zero-shot cancer diagnostic tasks. Notably, for cancer detection, KEEP demonstrates an average sensitivity of 89.8% at a specificity of 95.0% across 7 cancer types, significantly outperforming vision-only foundation models and highlighting its promising potential for clinical application. For cancer subtyping, KEEP achieves a median balanced accuracy of 0.456 in subtyping 30 rare brain cancers, indicating strong generalizability for diagnosing rare tumors.

译文排队中，当前展示来源原文。

license:mit
上下文窗口来源未披露
输入 → 输出待核验 → 待核验
模型权重待核验
档案更新时间2026/10/29 22:45:37
OVERVIEW

模型介绍

**KEEP** (**K**nowledg**E**-**E**nhanced **P**athology) is a foundation model designed for cancer diagnosis that integrates disease knowledge into vision-language pre-training. It utilizes a comprehensive disease knowledge graph (KG) containing 11,454 human diseases and 139,143 disease attributes, such as synonyms, definitions, and hierarchical relationships. KEEP reorganizes millions of publicly available noisy pathology image-text pairs into 143K well-structured semantic groups based on the hierarchical relations of the disease KG. By incorporating disease knowledge into the alignment process, KEEP achieves more nuanced image and text representations. The model is validated on 18 diverse benchmarks with over 14,000 whole-slide images (WSIs), demonstrating state-of-the-art performance in zero-shot cancer diagnosis, including an average sensitivity of 89.8% for cancer detection across 7 cancer types. KEEP also excels in subtyping rare cancers, achieving strong generalizability in diagnosing rare tumor subtypes. We present benchmark results for a range of representative tasks. A complete set of benchmarks can be found in the paper. These results will be updated with each new iteration of KEEP. Validated on 18 diverse benchmarks with more than 14,000 whole slide images (WSIs), KEEP achieves state-of-the-art performance in zero-shot cancer diagnostic tasks. Notably, for cancer detection, KEEP demonstrates an average sensitivity of 89.8% at a specificity of 95.0% across 7 cancer types, significantly outperforming vision-only foundation models and highlighting its promising potential for clinical application. For cancer subtyping, KEEP achieves a median balanced accuracy of 0.456 in subtyping 30 rare brain cancers, indicating strong generalizability for diagnosing rare tumors.

主要特点

特点摘要待依据来源补齐，不凭模型名称推断能力。

局限与注意事项

暂无足够来源支持具体缺点结论。请重点验证实际任务表现、时延、数据政策、许可与版本生命周期。

PRICING & COST

来源报价与费用分析

同一模型在不同渠道、地区和配置下可能采用不同价格。下表独立保留各渠道报价，不将渠道价格视为厂商官方统一价格。

来源 / 渠道输入输出计费单位采集时间
暂未取得可核验报价，请查阅来源渠道。

按月估算基础 Token 费用

—

预估不包含缓存优惠、阶梯定价、多模态附加费用、网络检索、税费及推理额外输出。

INDEPENDENT BENCHMARKS

公开评测与运行配置

暂无已采集的可核验公开评分。模型未上榜不代表能力较低。

查看完整已收录榜单 →

常见问题

开放权重是否代表可以免费商用？

不一定。应核对具体版本许可证、商用门槛和使用政策。自部署还会产生算力和维护成本。

这些价格是实时结算价格吗？

不是实时结算价格，而是带采集时间的来源报价快照。请到对应渠道核对当前版本、区域、折扣和计费方式。

资料来源与可追溯记录

huggingface · Astaxanthin/KEEP ↗2026/10/29 11:19:59
huggingface · enrich:5354a51e-6ca1-4706-82fd-0180e241b209 ↗2026/10/29 22:45:37

许可证：mit。模型介绍与第三方评测均以原来源的具体版本和方法为准。